Publications

https://updikelab.mdibl.org/?page_id=127

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Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans.  Reed, K.J., Svendsen, J.M., Brown, K.C., Montgomery, B.E., Marks, T.N., Vijayasarathy, T., Parker, D.M., Osborne-Nishimura, E., Updike, D.L., Montgomery, T.A., Nucleic Acids Research. Dec 24, 2019.

Quelling germ cell pluripotency on the genital ridge.  Updike, D.L., PNAS Dec 2019, 116(51)25374-5.

Germline maintenance through the multifaceted activities of GLH/Vasa in Caenorhabditis elegans. Marnik, E.A., Fuqua, J.H., Sharp, C.S., Rochester, J.D., Xu, E.L., Holbrook, S.E., & Updike, D.L. Genetics. Nov 2019. 213(3):..

Membraneless organelles: P granules in Caenorhabditis elegans.  Marnik, E.A., & Updike, D.L. Traffic. 2019 Jun:20(6):373-379.

Andralojc, K.M., Campbell, A.C., Kelly, A.L., Terrey, M., Tanner, P.C., Gans, I.M., Senter-Zapata, M.J., Khokhar, E.S., & Updike, D.L. (2017) ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans. PLoS Genetics 13(2): e1006611.

Rochester, J.D., Tanner, P.C., Sharp, C.S., Andralojc, K.M., & Updike, D.L. (2017) PQN-75 is expressed in the pharyngeal gland cells of Caenorhabditis elegans and is dispensable for germline development. Biology Open 6(9): 1355-1363.

Coffman, J.A., Rieger, S., Rogers, A.N., Updike, D.L., & Yin, V.P. (2016) Comparative biology of tissue repair, regeneration and aging. npj Regenerative Medicine.

Kelly, A. L., Senter-Zapata, M. J., Campbell, A. C., Lust, H. E., Theriault, M. E. and Andralojc, K. M., & Updike, D.L.  (2015). A forward genetic screen for suppressors of somatic P granules in C. elegans. G3 (5):2209-2215.

Campbell A.C. & Updike D.L.  (2015) CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline. Development, 142(10) 1745-1755.

Strome S. & Updike D.L.  (2015) Specifying and Protecting Germ Cell Fate. Nature Reviews Molecular Cell Biology, 16(7), 406-416.

Updike D.L., Knutson A.K., Egelhofer T.A., Campbell A.C., Strome S. Germ-Granule Components Prevent Somatic Development in the C. elegans Germline. Current Biology (2014).

Updike, D. L., Hachey, S. J., Kreher, J. & Strome, S. P granules extend the nuclear pore complex environment in the C. elegans germ line. The Journal of cell biology 192, 939–48 (2011).

Updike, D. L. & Strome, S. P granule assembly and function in Caenorhabditis elegans germ cells. J Androl 31, 53–60 (2010).

Updike, D.L., Strome, S. (2009) A Genome-wide RNAi Screen for Genes that Affect the Stability, Distribution, and Function of P granules in C. elegans. Genetics. 183(4):1397-419.

Sheaffer, K., Updike, D.L., Mango, S.E. (2008) The Target of Rapamycin Pathway Antagonizes pha-4/FoxA to Control Development and Aging. Curr Biol. 18(18); 1355-64.

Updike, D.L., Mango, S.E. (2007) Genetic suppressors of C. elegans pha-4/FoxA identify the predicted AAA helicase ruvb-1/RuvB. Genetics. 177(2); 819-833.

Updike, D.L., Mango, S.E. (2006) Temporal Regulation of Foregut Development by HTZ-1/H2A.Z and PHA-4/FoxA. PLoS Genetics. 2(9):1500-1510.

Kaltenbach, L.S., Updike, D.L., Mango, S.E. (2005) Contribution of the amino and carboxyl termini for PHA-4/FoxA function in Caenorhabditis elegans. Dev Dyn. 234(2):346-54.

Kominsky, D.J., Brownson, M.P., Updike, D.L. and Thorsness, P.E. (2002) Genetic and biochemical basis for viability of yeast lacking mitochondrial genomes. Genetics. 162(4):1595-604.

Hanekamp, T., Rebbapragada, I., Fisher, E.M., Seebart, C., Darland, M.R., Coxbill J.A., Updike D.L. and Thorsness, P.E. (2002) Maintenance of mitochondrial morphology is linked to maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Genetics. 162(3):1147-56.

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